Receptor,Stem Cell Factor
《英文msh詞典》Receptor,Stem Cell Factor
[同義詞] Receptor,Stem Cell Factor
[主題詞] Proto-Oncogene Protein c-kit
[中文釋義] 受體,干細胞因子
[英文釋義] A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic,gonadal,and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM,while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.
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